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After ejaculation, the body releases an enzyme called PDE-5, which breaks down cGMP causing the loss of the erection. Viagra, and other ED medicines, work by inhibiting the effect of PDE-5 thus increasing the blood flow to the penis and making it easy to gain and maintain an erection.
To treat erectile dysfunction-ED, take this drug by mouth as directed by your doctor, usually as needed. Take sildenafil at least 30 minutes, but no more than 4 hours, before sexual activity (1 hour before is the most effective). Do not take more than once daily.
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